NDUFA1 is a subunit of the enzyme NADH dehydrogenase (ubiquinone), the largest of the respiratory complexes. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. ND1 is a shorter form of NADH Dehydrogenase Subunit 1. and Facultative Anaerobic Eukaryotes based on Multiple Lineages of the Mitochondrial Gene NADH dehydrogenase subunit 1 (ND1) by Lynne van Herwerden, David Blair and Takeshi Agatsuma [7].This study invoked us … Of the 44 subunits, seven are encoded by the mitochondrial genome. The highly conserved two-domain structure suggests that this feature is critical for the protein function and that the hydrophobic domain acts as an anchor for the NADH dehydrogenase (ubiquinone) complex at the inner mitochondrial membrane. Preliminary data : … This study aimed to confirm the interactive effects between ND 25178 C > A and clinical risk factors on the susceptibility of essential hypertension in Chinese general population. Novel ND1 mutations responsible for maternally inherited nonsyndromic hearing loss We have characterized a wheat mitochondrial gene, designated nad7, capable of encoding a 394-amino acid subunit of the respiratory chain NADH dehydrogenase complex. Target-specific ELISA kits are available from a variety of manufacturers and can help streamline your immunodetection experiments. mitochondrial respiratory chain complex I, mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, GRCh38: Ensembl release 89: ENSG00000125356, "Entrez Gene: NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa", "Integration of cardiac proteome biology and medicine by a specialized knowledgebase", "NDUFA1 - NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1", "7 binary interactions found for search term NDUFA1", "Human mitochondrial complex I in health and disease", "The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria", "Species-specific and mutant MWFE proteins. The p49/STRAP and NDUFAB1 proteins interacted and co-localized with each other in the cell. Complex I transfers electrons to coenzyme Q10 after the electrons have passed through a series of redox groups, including FMN and six iron–sulfur clusters. Complex I functions in the transfer of electrons from NADH to the respiratory chain. Product citations. [5] The NDUFA1 gene produces an 8.1 kDa protein composed of 70 amino acids. NADH dehydrogenase in Neurospora crassa contains myristic acid covalently linked to the ND5 subunit peptide. Catalog Number: PHY1077S Size: 150 µg Confirmed reactivity: Arabidopsis thaliana Database Access Number: ATMG00510. Triticum aestivum (Wheat) Status. Scanlon DP, Bah A, Krzeminski M, Zhang W, Leduc-Pessah HL, Dong YN, Forman-Kay JD, Salter MW. McFadden CS, France SC, Sánchez JA, Alderslade P. Mol Phylogenet Evol. Complex I functions in the transfer of electrons from NADH to the respiratory chain. Research reagents for NADH DEHYDROGENASE SUBUNIT 6.  |  The discovery of new NADH dehydrogenase subunits and the polynucleotides encoding them provides a means to investigate mitochondrial respiratory mechanisms under normal and disease conditions and satisfies a need in the art by providing new diagnostic or therapeutic compositions useful in the treatment or prevention of cancer and immune disorders. NDUFA1 is one of a… Data Sheet-PHY1099S Size: (484.93 KB) Data Sheet-PHY1099S: Qty: Add to Cart. 39 kD / Anti-NADH dehydrogenase subunit 39kD, mitochondrial antibody. NADH:ubiquinone oxidoreductase is the largest of the respiratory complexes. 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